| Player, School | Gms | Comp | Att | INT | Yards | TD |
| Cody Fuller, Bluefield | 4 | 48 | 75 | 2 | 712 | 7 |
| Nathan Grimmett, Summers County | 3 | 37 | 65 | 1 | 694 | 7 |
| Will Fenton, Fayetteville | 4 | 37 | 58 | 1 | 660 | 11 |
| Tate Mayes, Nicholas County | 4 | 25 | 52 | 2 | 494 | 10 |
| Josh Morgan, Westside | 4 | 26 | 47 | 1 | 407 | 3 |
| Elijah Collier, Mount View | 3 | 20 | 36 | 0 | 293 | 3 |
| Joseph Cantley, Shady Spring | 4 | 29 | 69 | 2 | 256 | 1 |
| Hunter Bevins, Greenbrier West | 3 | 19 | 43 | 2 | 250 | 0 |
| Curtis Gray, Midland Trail | 4 | 14 | 29 | 1 | 232 | 6 |
| Sutton Radford, Woodrow Wilson | 3 | 8 | 22 | 1 | 222 | 2 |
| Devin Persinger, Greenbrier East | 4 | 6 | 15 | 3 | 197 | 2 |
| Shane Lipps, Richwood | 3 | 18 | 45 | 3 | 170 | 1 |
| Christian Shafer, Princeton | 4 | 8 | 12 | 0 | 108 | 1 |
| Evan Beasley, James Monroe | 3 | 3 | 12 | 0 | 105 | 1 |
| Jake Cannady, Wyoming East | 4 | 5 | 28 | 7 | 80 | 0 |
| Seth Ross, Wyoming East | 4 | 2 | 15 | 1 | 80 | 0 |
| Hunter Hall, Wyoming East | 1 | 5 | 5 | 0 | 74 | 0 |
| Jacob Bailey, Liberty | 3 | 4 | 11 | 0 | 66 | 3 |
| Tyler Haga, Independence | 4 | 5 | 11 | 1 | 65 | 1 |
| Hunter Weis, Greenbrier East | 4 | 7 | 18 | 0 | 63 | 0 |
| Jared Hamm, Princeton | 4 | 7 | 17 | 0 | 60 | 1 |
| Keith Sexton, Shady Spring | 4 | 7 | 11 | 1 | 60 | 0 |
| Dakota Shreve, Oak Hill | 2 | 5 | 13 | 1 | 51 | 0 |
| Adam Falbo, Valley | 3 | 5 | 15 | 2 | 41 | 0 |
| William Woods, Meadow Bridge | 4 | 2 | 12 | 2 | 30 | 0 |